Cortex Sells Selected AMPAKINE Compounds And Rights To Respiratory Depression Indication To Biovail

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Cortex Pharmaceuticals, Inc. (OTCBB: CORX) proclaimed that it has entered into an arrangement with Biovail Laboratories International SRL (”Biovail”) in which Biovail acquired sure AMPAKINE compounds and the rights to the apparent filing for gasmasky slump and vaso-occlusive crises associated with sickle cadre disease. The dealing with Biovail includes a leverage damage of $10,000,000 and extra payments of up to $15,000,000 based upon outlined clinical maturation milestones.

The correspondence includes the carry-over of rights to Biovail for sure AMPAKINE compounds, including the Phase II intensify CX717, the presymptomatic compounds CX1763 and CX1942, and the injectable dose manikin of CX1739 and the indicant of gasmasky impression. Specifically, the arrangement allows Cortex to hold its rights to non-injectable dose forms of CX1739 for all uses international of gasmasky imprint. Biovail testament appropriate Cortex to extend to prosecute the handling of quietus apnea for which a clinical run is presently afoot.

The dealings follows the earliest results from two of the Company’s Phase IIa studies in which disposal of CX717 prevented the onslaught of gasmasky imprint induced by an opioid, piece preserving the opioid’s pain-relieving effects. “We are pleased that Biovail has accepted the potentiality of our AMPAKINE engineering,” commented Mark A. Varney, Ph.D., President and CEO of Cortex. “We trust the engineering may finally be utilitarian in reversing or preventing gasmasky slump in patients undergoing operative procedures.”

Cortex retains all rights to the non-acquired AMPAKINE compounds for handling of neurodegenerative diseases and psychiatrical diseases which historically bear been contribution of its portfolio. “As a termination of this dealing, we bequeath be in the situation to proceed the viva Phase IIa kip apnea test with CX1739 and to enlightened a Phase II clinical tribulation for the discussion of ADHD identical presently,” commented Mark A Varney. “Additionally, we are push forrader to break the CX2007 and CX2076 serial of compounds and motility one of those analogs into the clinic as presently as potential.”

SunTrust Robinson Humphrey served as fiscal consultant to Cortex.

Cortex leave innkeeper a league cry on March 29, 2010 at 1:30 PM Pacific Daylight Time to discourse the dealings with Biovail. To approach the be league vociferation, U.S. and Canadian participants may dial (877) 407-8035 and outside participants may dial (201) 689-8035. A telephonic rematch of the league shout bequeath be useable for 30 years subsequently the song by dialing (877) 660-6853 (domesticated) or (201) 612-7415 (outside) and incoming chronicle numeral 286 and league birdcall routine 348077 when prompted.

Cortex Pharmaceuticals, Inc.

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